Metrorrhagia

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5 أقسام

شرح المدرسين

د. رغد الشديفات

د. رغد الشديفات

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Summary

Metrorrhagia, or intermenstrual bleeding, is defined as irregular vaginal bleeding occurring outside of the expected menstrual period, varying from light spotting to heavy flow. Key symptoms include unexpected bleeding of varying color and intensity, often accompanied by pelvic pain, bloating, headaches, and fatigue. Common causes range from hormonal imbalances, contraceptive use, and uterine structural issues like fibroids or polyps, to pregnancy-related complications, certain medications, stress, and, in rarer cases, neoplasia. Management strategies depend on the cause and can involve medical treatments like hormonal therapy, NSAIDs, tranexamic acid, and iron supplements, or surgical interventions such as Dilation and Curettage (D&C), endometrial ablation, myomectomy, uterine artery embolization, hysteroscopic polypectomy, or hysterectomy, chosen based on the bleeding's cause, severity, and the patient's desire for future fertility.

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Overview

Definition: Commonly called intermenstrual bleeding, is vaginal bleeding that occurs at irregular intervals not associated with the menstrual cycle. The bleeding may range from light spotting to heavier-than-normal flow and can occur occasionally or persistently.

 

Note  

It differs from:

  • Menorrhagia: heavy or prolonged menstrual bleeding during expected periods
  • Menometrorrhagia: a combination of heavy and irregular bleeding, occurring both during and between periods
ملاحظة

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Symptoms of Metrorrhagia

Main symptoms

  • Bleeding or spotting at unexpected times in the menstrual cycle
  • Bleeding may range from light spotting to a flow heavier than normal menstruation
  • Color of blood can vary from dark brown to bright red

Associated Symptoms:

  • Lower abdominal or pelvic pain
  • Bloating
  • Headaches
  • Fatigue or weakness (especially with heavy or chronic bleeding)
  • Passage of blood clots or mucus
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Common Causes of Metrorrhagia:

  1. Hormonal Imbalances.
  2. Hormonal Contraceptives
  3. Uterine Structural Issues (e.g., Fibroids, Endometrial polyps, Adenomyosis)
  4. Pregnancy Related (e.g., Implantation bleeding, Miscarriage, Ectopic pregnancy)
  5. Infections (e.g., Pelvic inflammatory disease (PID), Cervicitis)
  6. Medical Conditions (e.g., PCOS, Hypo/hyperthyroidism, Coagulopathies)
  7. Neoplasia
  8. Medications (e.g., Anticoagulants (warfarin, aspirin), steroid) 
  9. Stress
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Managment

Medical Management
Treatment Indications
Hormonal Therapy Oral contraceptives, progestins, or levonorgestrel IUD to regulate cycles and reduce bleeding
NSAIDs Reduce menstrual flow and pain
Tranexamic Acid Antifibrinolytic that reduces heavy bleeding
Desmopressin For patients with mild bleeding disorders
Iron Supplements To treat or prevent iron-deficiency anemia due to chronic blood loss
Surgical or Interventional Procedures
Procedure Indications
Dilation and Curettage (D&C) Diagnostic and therapeutic for abnormal bleeding
Endometrial Ablation Destroys uterine lining; for women not desiring future fertility
Myomectomy Surgical removal of fibroids while preserving uterus
Uterine Artery Embolization (UAE) Minimally invasive; used to shrink fibroids
Hysteroscopic Polypectomy Removal of endometrial polyps
Hysterectomy Definitive treatment for recurrent or refractory bleeding; especially if malignancy is a concern
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